my-cart-icon svg-arrow-next svg-arrow-prev

Polyflora + Multifunction Probiotic with Akkermansia (Blood Type B)

Personalized probiotic for Blood Type B to support digestive health, immunity and weight loss. A blend of unique prebiotics + targeted probiotics + keystone postbiotic species, Akkermansia.

Select your blood type: O A B AB

Balance gut health with the improved Polyflora +.

Polyflora + was formulated by Dr. Peter D’Adamo to address the special needs of each blood type plus incorporate the keystone species Akkermansia, a weight loss enhancing and microbiome optimizing postbiotic bacteria.

Research shows that gut bacteria can differ by up to 50,000x between blood types, yet most people use a one-size-fits-all probiotic. That’s where Polyflora + comes in. Along with blood type friendly bacteria, Akkermansia plays a vital role in supporting the growth of virtually all other “friendly flora” in your microbiome.


“I've been following the research on Akkermansia for several years now. It is clearly a mandatory bacterial species if we are in need of metabolic support. Many of my overweight patients, when tested, actually have little or no Akkermansia at all in the microbiome.”

- Dr. Peter D’Adamo


  • Unique Prebiotics: Prebiotics selected for your blood type feed the good bacteria to help your microbiome thrive.
  • Targeted Probiotics: Blood type beneficial probiotics help balance the gut to aid digestion, immunity and overall wellness.
  • Keystone Postbiotic Akkermansia: Without this crucial piece, the whole ecosystem suffers. Akkermansia muciniphila strengthens digestive lining, locks in gut health and helps control all the elements of the microbiome.

Polyflora + for Blood Type B may help:

  • Promote gut balance using bacterial strains deemed beneficial for Type Bs
  • Optimize nutrient absorption and digestive health
  • Aid immune response and overall wellness
  • Support healthy weight loss

Polyflora + may be for you if:

  • You’ve tried other probiotics with no success
  • You’re on The Blood Type Diet but feel your gut health needs extra support
  • You have an imbalance of gut bacteria due to stress or medication, especially antibiotics
  • You experience frequent stomach discomfort, bloating, gas and irregularity
  • You’re looking to improve your overall digestive health and immunity

Dr. D’Adamo’s Polyflora + with Akkermansia helps support gut bacterial balance, intestinal permeability, immune health and weight loss. Discover probiotics, only better.

Our exclusive Polyflora + for Blood Type B includes:

Lactobacillus bulgaricus
Supports the Blood Type B microbiome as a resilient bacteria. L. bulgaricus is capable of withstanding low pH levels, making it ideal and resistant against stomach acid.

Saccharomyces cerevisiae
Helps to prevent bacterial overgrowth and promotes digestive regularity. Saccharomyces cerevisiae is also helpful for preventing growth of harmful dysbiotic bacteria.

Akkermansia muciniphila postbiotic
Helps strengthen the gut lining and works to protect individuals from an affliction known as leaky gut or intestinal permeability. Akkermansia naturally lives in the mucous of the gut barrier where its consumption of mucins stimulates gut cells to produce more mucins, a feedback process that ultimately engenders a robust gut lining to support the entire microbiome.

Dosage & Information

Directions: Two (2) capsules two (2) times daily with food as a dietary supplement or as directed by physician.

120 vegetarian capsules

Is this product vegetarian? Yes

Usable by all types? No

This 100% vegetarian product contains no sugar, salt, gluten, wheat, yeast, corn, soy, eggs or dairy, no preservatives, color or flavors, and no artificial ingredients.


Get More from Your Supplements with D’Adamo Personalized Nutrition

Polyflora + is made for each blood type and manufactured in the USA using GMP (Good Manufacturing Practices) in a facility certified through the Natural Products Association, with an “A” compliance rating. It does not contain any of the most common food allergens. D’Adamo Personalized Nutrition also offers other supplements and vitamins custom-made for your body’s needs.

Step 1: Understand how to eat for your blood type. Step 2: Personalize your supplement routine. D’Adamo Personalized Nutrition makes it easy to begin your journey towards better health and wellness.

Returns Policy

You may return most new, unopened items within 30 days of delivery for a full refund. We'll also pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.).

You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).

If you need to return an item, simply login to your account, view the order using the "Complete Orders" link under the My Account menu and click the Return Item(s) button. We'll notify you via e-mail of your refund once we've received and processed the returned item.


We can ship to virtually any address in the world. Note that there are restrictions on some products, and some products cannot be shipped to international destinations.

When you place an order, we will estimate shipping and delivery dates for you based on the availability of your items and the shipping options you choose. Depending on the shipping provider you choose, shipping date estimates may appear on the shipping quotes page.

Please also note that the shipping rates for many items we sell are weight-based. The weight of any such item can be found on its detail page. To reflect the policies of the shipping companies we use, all weights will be rounded up to the next full pound.


No. Polyflora Pre/Probiotic is a blood-type specific supplement that supports overall gut health and intestinal balance. It is a personalized supplement for each blood type with formulas available for each blood type: O, A, B and AB.

You must know your blood type to find the Polyflora + formula that’s best for you. The Home Blood-Typing Kit is an easy way to get started. It works in under 10 minutes to reveal your results right at home.

Directions: Two (2) capsules two (2) times daily with meals as a dietary supplement or as directed by a physician. Polyflora + helps promote healthy digestion and supports your gut microbiome with a blood-type-specific probiotic formula.

This depends on what you’re looking to achieve, but on average it takes several weeks for your probiotic to make a difference.

Minimum Duration: Test a probiotic for at least 2-4 weeks before assessing its effectiveness. Individual Response: Some may notice benefits sooner, but consistent use over a few weeks provides a better evaluation. Adjust as Needed: If no improvement is observed over time, consulting a healthcare professional for guidance is advisable.

Much like Polyflora + is not one-size-fits-all, each individual’s goals may vary along with the duration. Acute Issues: Relief for gut discomfort and bloating may be noticed in as little as a few days. Ongoing Issues: Improvements to bigger problems caused by gut bacteria imbalance such as nutrient malabsorption and weight management can take several weeks to months. Individual Variation: Response time varies based on factors such as the probiotic strain, dosage, individual health and lifestyle choices.

Consistency Matters: Regular and consistent use of probiotics is often essential for sustained benefits. Remember, results vary but it’s important to give your probiotics time to help balance your gut microbiome.

Polyflora + combines unique prebiotics and targeted probiotics to support digestive health. Dr. Peter D’Adamo selected bacteria beneficial for each blood type plus added Akkermansia postbiotic, a keystone bacterium. Akkermansia postbiotic provides support for the growth of virtually all other “friendly flora” in your microbiome; without it, the whole ecosystem suffers.

  • Prebiotics are nutrients that foster the growth of healthy intestinal flora, AKA probiotics. Together, they work synergistically to assist in proper digestive system function.
  • Probiotics are beneficial bacteria that aid in the microbiome’s intestinal balance to support healthy digestion and wellness.
  • As a postbiotic, Akkermansia provides bioactive compounds to strengthen the gut lining. These bioactive compounds hold and support the structure, and assist in overall gut health and weight loss.

Prebiotics and probiotics work together. Prebiotics act as a food source for the healthy bacteria in your stomach AKA probiotics. The result is stronger “good bacteria” in the gut.

There are many benefits of taking prebiotics and probiotics:

  • Assists in gut bacteria balance to promote healthy digestion
  • May decrease bloating, gas and upset stomach
  • Aids in better nutrient absorption and weight control
  • Helps support immune system function
  • And more

When scientists culture a desirable bacteria they can then harvest its bioactive components for therapeutic use. This is known as a postbiotic. Postbiotic supplementation is very much at the forefront of microbiome technology as it provides the exact therapeutic effect of the desired bacteria.

Akkermansia’s full name is Akkermansia muciniphila, which means “mucin loving.” That’s because Akkermansia's favorite meal is the mucous membrane of your intestinal lining. But in exchange for food, Akkermansia’s mucin consumption actually stimulates increased mucin production by intestinal cells, leaving a fresh and regularly regenerated gut lining.

This robust gut lining is a critical protector of the immune system that lies right below the single-cell lining of the gut. A thick mucin layer adds additional protection between the food and bacterial antigens and the underlying immune system.

Akkermansia also promotes a "tolerogenic" immune system. It secretes enzymes that engender a more neutral immune response, allowing us to be less reactive to foods we eat and more tolerant of minor insults that we incur on a daily basis.

Akkermansia is a metabolic celebrity. This bacteria supports proper insulin/glucose response, and is a "leanness" associated bacteria. This association is likely due to Akkermansia's role promoting GLP-1 secretion, an incretin hormone that promotes insulin sensitivity and healthy blood sugar levels.

It's very difficult to stabilize Akkermansia as an encapsulated probiotic that will survive the manufacturing process. However in our Polyflora + it's available as a postbiotic, where its bioactive ingredients have been extracted and incorporated into the formula, allowing for higher concentrations than would be possible from the live bacteria itself. And so as a postbiotic, the Akkermansia in our Polyflora + is more stable and able to provide all its inherent benefits.

The Blood Type Diet is a lifestyle guide that helps you determine which foods are best for you based on your genetic makeup. Naturally occurring proteins from foods on your Avoid list (AKA lectins) can attach to your digestive tract and wreak havoc, causing inflammation, gas, bloating, water retention, weight gain, headaches, fatigue, hormonal imbalance and more.

In addition, your ABO profile provides insight on how you can best handle stress, manage weight and plan strategies for overall health and wellbeing. Dr. Peter D’Adamo outlines the basics in his New York Times best-selling book, Eat Right 4 Your Type.

Get started with The Blood Type Diet Intro Pack or explore testimonials from our community around the world.