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Polyflora - Pre/Probiotic (Blood Type O)

49 Customer Reviews Write a Review

Personalized probiotic with flora specifically beneficial for Blood Type O. Also includes prebiotic synergists to strengthen digestive health.

Select your blood type: O A B AB

We've personalized probiotics.

Studies have documented the clear role our ABO blood type and secretor status play in determining the makeup of our microbiome the total population of bacteria that live within our digestive tract. Because the foods you eat react chemically with your blood type, personalizing both your food, with The Blood Type Diet, and your supplements, with the probiotics and prebiotics in Polyflora O, will allow your body to support healthy digestion.

Probiotics are acid bacteria organisms and cultured food products that support healthy intestinal balance of the microbiome. Prebiotics are nutrients that help support growth of healthy intestinal flora. Our personalized formulation of probiotics and prebiotics support your digestion.

Dr. Peter D'Adamo's revolutionary Polyflora O is a personalized probiotic with flora specifically beneficial for Blood Type O, plus prebiotic synergists to strengthen digestive health.

  • Supports the healthy intestinal balance of the microbiome
  • Strengthens digestive health
  • Promotes overall gut health using specific strains deemed beneficial for Type Os

Our exclusive Polyflora O combination includes:

Streptococcus thermophilus
Supports immune function and improve digestion. A powerful probiotic and beneficial flora for Blood Type O, S. thermophilus has been shown to improve digestive symptoms.

Lactobacillus rhamnosus
Supports healthy cholesterol metabolism and weight management. One of the most researched probiotics, L. rhamnosus has been shown to improve constipation and/or diarrhea in adults and children.

Saccharomyces boulardii
Helps to prevent bacterial overgrowth and promotes digestive regularity. A resilient species, It is also helpful for preventing growth of harmful dysbiotic bacteria.

Click the Play button to hear to Dr. Peter J. D'Adamo discuss Polyflora.

Specially formulated for you, Polyflora O personalized probiotics promote healthy digestion and support the unique composition of the Blood Type O microbiome.

Dosage & Information

For maximum benefit: take two (2) capsules twice daily with meals
(As a dietary supplement or as directed by a physician)

120 vegetarian capsules
Is this Product Vegetarian? Yes

Does not contain: sugar, sugar, salt, gluten, wheat, corn, soy, eggs, dairy, preservatives, color, flavors or artificial ingredients

For California Residents

Prop 65 Warning

WARNING: Consuming this product can expose you to Lead, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to


Recommended Reading

3 Keys to Gut Harmony The Blood Type Diet Fermented Foods Bugs and Blood Types
Write a Review
  • Polyflora O

    Posted by G Radovanovich on Feb 19th, 2021

    I have used this for about a year and after a serious throat. Infection that required antibiotics. I also have other digestive issues . I like this but it is ridiculously expensive and I am no longer buying it. Too bad it worked. Well.

  • Polyfora

    Posted by Anonymous on Aug 30th, 2020

    I love this probiotic, easy on the system, much healthier digestion within two weeks if following the O protocols and taking polyglots!

  • I definitely recommend this product

    Posted by Dora Ponnequin on Jul 31st, 2020

    I have been using this product quite a while, it keep my digestive system and colon is more balance

  • Polyflora

    Posted by Gayle Mio on May 17th, 2020

    I had run out of Polyflora so I bought some probiotics from the ... but I started to suffer with digestive issues. Am now on my Polyflora and all is well again.

  • Polyflora

    Posted by Nilda Cruz on May 14th, 2020

    This is perfect for my blood type O ! I will not buy any other because this one makes me feel that I am, comfort, balanced and I feel my digestion is processing properly. thank you Dr. D’adamo

  • Taste

    Posted by Bill Cartledge on Dec 5th, 2019

    Have not noticed any significant effect whilst taking this supplement.

  • Polyflora

    Posted by Diane Roy on Jul 14th, 2019

    This is the best probiotic I've used. My body knows the difference between these and others I have tried in the past. Strongly recommend.

  • Best Probiotic

    Posted by Chamaine Collazo on May 31st, 2019

    This is a best probiotic I've ever had. I take it daily prior to my first & last meal. It's not necessary to keep refrigerated but I do anyway.

  • Oops, had a capsule empty.

    Posted by Karen on Apr 27th, 2019

    Didn’t expect this but I guess it happens. I’m assuming it’s automated filling and fell through. Better quality control in the beginning I hope it’s filled by weight and not the number. I have a pic, if you’d like.

  • Happy Guts

    Posted by Bea Stachiw on Apr 8th, 2019

    I have begun to use the Polyflora instead of my other probiotic and find it works better for me and will continue it's use.

  • Not sure.

    Posted by Anonymous on Apr 6th, 2019

    After taking the Polyflora O for 1 month, I am not sure if there is much improvement in my problem with tummy bloating over the other probiotic that I had been taking. I'm not sure that I will continue ordering as the price is substantially higher plus the added cost of shipping. I guess I can only know when I stop taking the product. I have cut out all sugar, yeast and most fruit and hoped that by adding the prebiotic element with the probiotic, my problem would be solved. I have been on the blood type diet for over a decade, eventually finding that I was O non-secretor, so made those changes in my diet but have still consistently had a problem with bloating. Maybe the fact that I am 78 years old is a factor. I have to be very careful how I spend my dollars at this point. Otherwise, have been happy with the changes that discovery of the blood type diet has made in my life.

  • Probiotic

    Posted by Dee on Apr 5th, 2019

    I will have to say that this project does not have enough probiotics. I tried this because I triy to follow the blood type diet. However I had to go back to my previous probiotic that had 30 billion and more lactobacillus products. I started to get a yeast infection again. Sorry

Practitioner Technical Information

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Polyflora O TRM

Returns Policy

You may return most new, unopened items within 30 days of delivery for a full refund. We'll also pay the return shipping costs if the return is a result of our error (you received an incorrect or defective item, etc.).

You should expect to receive your refund within four weeks of giving your package to the return shipper, however, in many cases you will receive a refund more quickly. This time period includes the transit time for us to receive your return from the shipper (5 to 10 business days), the time it takes us to process your return once we receive it (3 to 5 business days), and the time it takes your bank to process our refund request (5 to 10 business days).

If you need to return an item, simply login to your account, view the order using the "Complete Orders" link under the My Account menu and click the Return Item(s) button. We'll notify you via e-mail of your refund once we've received and processed the returned item.


We can ship to virtually any address in the world. Note that there are restrictions on some products, and some products cannot be shipped to international destinations.

When you place an order, we will estimate shipping and delivery dates for you based on the availability of your items and the shipping options you choose. Depending on the shipping provider you choose, shipping date estimates may appear on the shipping quotes page.

Please also note that the shipping rates for many items we sell are weight-based. The weight of any such item can be found on its detail page. To reflect the policies of the shipping companies we use, all weights will be rounded up to the next full pound.

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