Explorers are typically mesomorphs, possessing a low to medium body fat percentage, a high metabolism, and a large amount of muscle mass and muscle size. They can be rather large-boned, and the men tend to have asymmetrical, chiseled, craggy faces. Their trunk length is usually longer than their total leg length and their upper legs are usually longer than their lower. Explorers can be virtually any ABO blood group, but have a higher than average incidence of the non-secretor status and are often also Rhesus negative (Rh-) blood type. Left-handers are also more commonly found in this Epigenotype.
Explorers are very often medical enigmas. They can be challenging to diagnose, since nothing apparent or obvious presents itself as a problem. Physically, they may appear to be in good health, but will complain of a sudden loss of energy or a sudden inability to tolerate a certain food, supplement, or drug. Explorer women often suffer from chronic yeast infections or heavy periods. Blood tests often reveal anemia or other blood disorders. Caffeine sensitivity is a hallmark of Explorers because they are almost always what geneticists call 'slow acetylators' - a fancy way of saying drugs spend a long time in their livers, going round and round, when they should just get processed and eliminated.
Explorers have problems detoxifying drugs, carcinogens, and various compounds that have been introduced into the environment by artificial means, such as pesticides, fertilizers, and hydrocarbons. Because of these issues, Explorers can be quite chemically sensitive, and often react negatively to the 'typical doses' of drugs, antibiotics, and even vitamins and minerals. When using these medicines they should always start with the lowest doses and gradually work their way upward.